MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development
نویسندگان
چکیده
منابع مشابه
MOZ regulates B-cell progenitors and, consequently, Moz haploinsufficiency dramatically retards MYC-induced lymphoma development.
The histone acetyltransferase MOZ (MYST3, KAT6A) is the target of recurrent chromosomal translocations fusing the MOZ gene to CBP, p300, NCOA3, or TIF2 in particularly aggressive cases of acute myeloid leukemia. In this study, we report the role of wild-type MOZ in regulating B-cell progenitor proliferation and hematopoietic malignancy. In the Eμ-Myc model of aggressive pre-B/B-cell lymphoma, t...
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For real numbers C, T 1 , T 2 , ... we find all solutions µ to the stochastic fixed point equation W j≥1 T j W j + C, where W, W 1 , W 2 , ... are independent real-valued random variables with distribution µ and means equality in distribution. All solutions are infinitely divisible. The set of solutions depends on the closed multiplicative subgroup of R * = R\{0} generated by the T j. If this g...
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ژورنال
عنوان ژورنال: Blood
سال: 2015
ISSN: 0006-4971,1528-0020
DOI: 10.1182/blood-2014-08-594655